ABSTRACT
Background: PGE2 gel (cerviprime) not only helps in cervical ripening but also sensitizes the uterine musculature to physiological PGE2 for generation and maintenance of uterine contractions. In the present study the efficacy of PGE2 intracerival gel for ripening and induction of labour has been reported.Methods: This is a randomized prospective study of 80 cases admitted to the labour room during period of 2 years i.e. March 2017 to March 2019 in Department of Obstetrics and Gynecology, KBNIMS, Gulbarga, Karnataka. All patients had clear indications for termination of pregnancy. The initial bishop score determined prior to induction by pelvic examination. Under aseptic precautions PGE2 endocervical gel was instilled. The results analyzed for successful ripening, induction delivery interval, results in primigravida and multigravida with single instillation or reinstallation if required, mode of delivery and maternal and perinatal complications.Results: The present study of 80 cases showed that a single application of intracervical PGE2 gel caused favorable changes in cervix by increasing Bishop score and shortened induction delivery interval with minimal side effects. Successful ripening with single application was achieved in 92.5% of cases (primi 42.5% and multi 50%). Only 6.25% of primi's and 1.25% of multi’s required reinstallation of PGE2 gel. Successful induction was achieved in 47.5% primi's and 50% multi’s i.e. 97.5% cases.Conclusions: The study concludes that single low dose intracervical PGE2 (cerviprime) gel proved to a safe, reliable and effective method for cervical ripening and induction of labour.
ABSTRACT
Background: Vulvovaginitis is a common unavoidable health problem encountered in a woman’s life. Because of its recurrent and persistent symptoms, it leaves a negative impact on the quality of woman’s life and its management poses a challenge. This study is aimed to analyse the clinical profile, clinical symptoms - presentations and various etiological agents in vulvovaginitis.Methods: A study of 125 cases of vulvovaginitis in the age group of 18-50 years was done. This study was based on the data collected like - age, parity, symptoms, clinical presentations and cytological findings. Speculum examination was done with the given consent and high vaginal swabs were taken for cytological study. Based on Amsel’s criteria bacterial vaginosis was confirmed, trichomoniasis by wet mount examination and candidiasis by culture study were confirmed.Results: The present study showed maximum incidence of vaginitis 63.2% among 21-30 years age group, more common in multiparous women 44.8% and vaginal discharge was the commonest symptom 88%. Cytological study showed 53.6% bacterial vaginosis {BV), 27.2% vulvovaginal candidiasis (VVC), 2.4% trichomoniasis and remaining 17% mixed infections like BV + VVC 15.2% and 1.6% BV + VVC + Trichomoniasis.Conclusions: All women of reproductive age should have mandatory regular evaluation for early detection and proper management of vulvovaginitis. Creating awareness among women improves their quality of life.